About Us

A personal note from Vladimir Fanshil & Eleanor Lyons

Live at Yours began in the most unexpected way — in our own living room. In 2020, when the world fell silent, we refused to believe that music should exist only on screens. So we gathered a handful of people, pulled the chairs close, and performed for twenty guests at a time. Those evenings were small, fragile, unforgettable — and they reminded us why we became musicians: to share something real, something human, something that only exists when people come together.

A New Way to Experience Music

In the first years, we travelled across NSW and the ACT, giving more than 50 performances in lounge rooms, coffee roasteries, tin sheds in the outback, art galleries, churches, synagogues and regional theatres.

It was in those intimate settings that we connected deeply with locals, listened to their feedback, and discovered what Australians truly value in live music: informal yet refined, relaxed yet deeply sincere, intimate yet world-class.

Those conversations shaped everything — from our welcoming tone to having no intervals, allowing the emotional arc to flow without interruption. This is how we crafted the ultimate listening experience we offer today: personal, natural and genuinely shared.

From a lounge room to a national stage

Live at Yours has now grown far beyond our living room — into concert spaces across Sydney, Melbourne, Adelaide, Canberra, Orange, Castlemaine and beyond — yet the essence remains unchanged.

Every venue is chosen for its story and atmosphere. Every performance is lit and shaped to feel close, warm and immersive. And every artist who joins us shares our belief in vulnerability, honesty and connection.

World-class artists, up close

Extraordinary artists, shared in intimate spaces — where every detail comes alive.

Richard Tognetti

Yamen Saadi

Alexander Gavrylyuk

Emily Sun

Elena Kats-Chernin

Andrew Haveron

Kristian Winther

Rosanna Rolton

Vatche Jambazian

Elina Faskhi

Stefanie Farrands

Simon Tedeschi

Committed to the next generation

As Live at Yours grows, so does our responsibility to young musicians. Through masterclasses, mentoring, and partnerships with ANAM and the Sydney Conservatorium, we help the next generation experience the same intimacy and inspiration that shaped our early years.

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Thank you for being part of this journey!
We can’t wait to welcome you — up close, and personal.

Tamoxifen Online In Australia? Let's Hit Pause Before You Click "Buy". Visit Our Pharmacy ↓

Tamoxifen in Australia: A Doctor’s Evidence-Based Review for Women and Men Over 30

If you or someone you love has been told the words “hormone receptor-positive breast cancer” or “high-risk breast lesion,” you already know the fear that follows. For Australians over 30, breast cancer is not a distant statistic — it is the most common cancer diagnosed in women, with around 20,000 new cases each year. Many patients ask me: “Is there a medicine that truly helps me stay alive longer without destroying my quality of life?” The answer, for millions of patients worldwide and thousands of Australians, is often tamoxifen. In this review, I will walk you through exactly how tamoxifen works, what it can and cannot do, what side effects to expect, and why it remains one of the most valuable medicines in oncology — and why you should feel confident discussing it with your doctor.

Attention: The Silent Threat and the Medicine That Fights Back

Hormone-sensitive breast cancer grows when oestrogen binds to receptors on cancer cells. Tamoxifen is not chemotherapy. It is a selective oestrogen receptor modulator (SERM) that blocks oestrogen from stimulating breast cancer cells. In early-stage, oestrogen receptor-positive (ER+) breast cancer, tamoxifen reduces the risk of recurrence by approximately 40–50% and reduces the risk of death by about 30% over 10 years. For women with high-risk benign breast disease such as atypical hyperplasia or lobular carcinoma in situ, tamoxifen reduces the risk of developing invasive breast cancer by up to 50%.

But you are not just a statistic. You are a person worried about nausea, heart health, allergies, immunity, and whether the medicine will fit into your daily life. I will address all of these concerns honestly, as I do with my own patients in my Australian practice.

Interest: The History, Science and Australian Availability of Tamoxifen

What is the history of tamoxifen? Tamoxifen was first synthesised in 1962 by scientists at Imperial Chemical Industries (ICI) in the United Kingdom, initially as a possible contraceptive. It failed as a contraceptive but was found to induce ovulation. Its true breakthrough came in the 1970s when clinical trials demonstrated powerful anti-oestrogen effects against breast cancer. It was approved in the UK in 1973 and later worldwide. By the 1980s and 1990s, large trials such as the Early Breast Cancer Trialists’ Collaborative Group confirmed its life-saving benefit. Today, tamoxifen is listed on the World Health Organization Model List of Essential Medicines and is available on the Pharmaceutical Benefits Scheme (PBS) in Australia, making it affordable for eligible patients.

How is tamoxifen metabolised? Tamoxifen is a prodrug. After you swallow a tablet, your liver enzymes — mainly CYP2D6 and CYP3A4 — convert tamoxifen into active metabolites, the most important being endoxifen. Endoxifen is up to 100 times more potent than tamoxifen itself at blocking the oestrogen receptor. This is why some medicines that inhibit CYP2D6, such as certain antidepressants (paroxetine, fluoxetine), may reduce tamoxifen’s effectiveness. In my practice, I always review your full medication list before starting tamoxifen. If you need an antidepressant, I choose one that does not strongly block CYP2D6, such as escitalopram or venlafaxine.

Who manufactures tamoxifen in Australia? Tamoxifen is widely available in Australia as both original and generic brands. Common Australian brands include:

These are available at virtually every Australian community pharmacy. The generic versions are clinically equivalent to the original brand and are usually the most cost-effective option for patients.

Desire: Real Answers to the Questions That Worry You Most

Can tamoxifen cause nausea?

Yes, nausea can occur, but it is usually mild and often settles within the first few weeks. In clinical practice, I find that fewer than 10% of patients report significant nausea. Taking tamoxifen with food or at bedtime dramatically reduces this symptom. If nausea persists, I prescribe a short course of an anti-nausea medicine such as metoclopramide or ondansetron. The key point: for most patients, nausea is a temporary inconvenience, not a reason to stop a potentially life-saving treatment.

Can tamoxifen cause a heart attack?

**Tamoxifen Brands Commonly Available in Australia**
Brand Name	Manufacturer / Supplier	Common Strengths	PBS Listed
Nolvadex-D	AstraZeneca / Generic distributors	10 mg, 20 mg	Yes
Genox	Aspen Pharmacare	10 mg, 20 mg	Yes
Tamoxifen Sandoz	Sandoz (Novartis)	10 mg, 20 mg	Yes
Tamoxifen Alphapharm	Alphapharm (Viatris/Mylan)	10 mg, 20 mg	Yes
Tamoxifen Teva	Teva Pharma Australia	10 mg, 20 mg	Yes

This is a common fear. The honest answer is: tamoxifen is not a direct cause of heart attacks. In fact, tamoxifen can lower LDL (“bad”) cholesterol and may have a modest protective effect on the heart in some postmenopausal women. However, tamoxifen does increase the risk of blood clots, including deep vein thrombosis (DVT) and pulmonary embolism, especially in women over 50, smokers, or those with a history of clotting. A blood clot can, very rarely, lead to a cardiac event, but tamoxifen has not been shown to significantly increase the rate of myocardial infarction itself. I always assess cardiovascular risk before prescribing. If you experience sudden chest pain, shortness of breath, severe leg swelling, or coughing blood, seek urgent medical care — but do not stop tamoxifen without speaking to your doctor.

What are the signs of an allergic reaction to tamoxifen?

Serious allergic reactions to tamoxifen are uncommon, but you must know the warning signs. Stop the medicine and call 000 or go to an emergency department if you develop:

Mild skin rashes may be managed with antihistamines, but any rash should be reported to your doctor. In over 20 years of practice, I have seen very few true allergic reactions to tamoxifen, and most were mild.

Is tamoxifen used for ovarian cancer?

Yes. Tamoxifen has a small but important role in ovarian cancer. It is most commonly used in recurrent or advanced epithelial ovarian cancer that is oestrogen receptor-positive, particularly in patients who have exhausted standard chemotherapy. It is also used in ovarian stromal tumours, such as granulosa cell tumours, which often express hormone receptors. In these settings, tamoxifen can provide disease control for months or years with a relatively gentle side-effect profile. If you have ovarian cancer and your tumour is hormone-sensitive, ask your oncologist whether tamoxifen is appropriate for you.

Does tamoxifen affect the immune system?

Tamoxifen is not an immunosuppressant. Unlike chemotherapy, it does not wipe out your white blood cells. In fact, research shows tamoxifen may have complex immunomodulatory effects — it can enhance natural killer (NK) cell activity and alter cytokine production, potentially helping the body’s own defence against cancer cells. You are not at meaningfully higher risk of everyday infections while taking tamoxifen. You can continue normal activities, travel, and receive vaccines. If you are concerned about immunity, maintain a balanced diet, exercise, and sleep — these matter far more than any effect from tamoxifen.

Side Effects and How We Manage Them

Action: Take Control of Your Health Today

Tamoxifen is not a “one-size-fits-all” drug, but for the right patient, it is one of the most effective, well-studied, and affordable cancer medicines ever developed. It has been used for over 50 years, is available on the PBS in Australia, and is manufactured by trusted companies such as Sandoz, Alphapharm, Aspen, and Teva. Whether you are a woman with ER+ breast cancer, a man with male breast cancer, someone with DCIS, or a patient with hormone-sensitive ovarian cancer, tamoxifen may offer you a real survival advantage.

**Common Tamoxifen Side Effects and Practical Australian Management Strategies**
Side Effect	How Common	What You and Your Doctor Can Do
Hot flushes / night sweats	Up to 60–70%	Dress in layers, avoid caffeine/alcohol, consider non-hormonal options such as venlafaxine or oxybutynin. Do not use oestrogen-based HRT.
Vaginal dryness / discharge	30–50%	Water-based lubricants, vaginal moisturisers, or low-dose local oestrogen pessaries after specialist review.
Irregular periods / menstrual changes	Common in premenopausal women	Discuss contraception — tamoxifen is not a contraceptive and can harm an unborn baby. Use barrier or non-hormonal methods.
Mood changes / fatigue	15–25%	Exercise, sleep hygiene, counselling, and sometimes a CYP2D6-compatible antidepressant.
Leg cramps / joint aches	10–20%	Magnesium supplements, stretching, adequate hydration. Severe pain needs review.
Increased risk of blood clots	1–2% absolute increase	Stop smoking, maintain healthy weight, move regularly on long flights. Seek urgent care for leg swelling or breathlessness.
Endometrial thickening / uterine cancer risk	Rare, ~0.2–0.5% per year	Report any abnormal vaginal bleeding immediately. Annual pelvic examination; ultrasound only if symptoms occur.

Your next step is simple: book an appointment with your GP or oncologist. Bring this article. Ask:

Do not let fear of side effects stop you from a medicine that could add decades to your life. In my practice, most patients tolerate tamoxifen well, and we manage side effects together. The risk of doing nothing — the risk of cancer recurrence — is far greater than the risk of taking tamoxifen under medical supervision.

This article is for general educational purposes and does not replace individual medical advice. Always consult your doctor before starting, stopping, or changing any medication.